SIRT6-IN-5 - CAS 891002-11-2

SIRT6-IN-5 (SIRT6 inhibitor 5) is a potent and selective SIRT6 inhibitor with an IC50 value of 34 μM.SIRT6-IN-5 is immunosuppressive and chemo-sensitizing, increases H3K9 acetylation and glucose uptake in cultured cells, and reduces T-cell proliferation.

Sirtuin

DNA Damage/DNA Repair, Chromatin/Epigenetic

891002-11-2

0.9923

C19H14N2O6

366.32

N(C(=O)C1=CC=C(NC(=O)C2=CC=CO2)C=C1)C3=CC(C(O)=O)=C(O)C=C3

-20°C

Ice Packs

Small Compound