γ-Sitosterol - CAS 83-47-6

γ-Sitosterol acts as an inhibitor of c-Myc. It suppresses the proliferation of cancer cells MCF-7 and A549, with IC50 values of 240.73 μg/mL and 696.6 μg/mL, respectively. γ-Sitosterol induces cell cycle arrest at the G2/M phase and triggers apoptosis (apoptosis) . Additionally, it upregulates the expression of cyclin B/E [cyclin B/E].

Apoptosis, c-Myc

Cell Cycle/Checkpoint, Apoptosis

83-47-6

C29H50O

414.707

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@@H](C(C)C)CC)C)[H])[H]

-20°C

Ice Packs

Natural Product