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Sivelestat sodium tetrahydrate - CAS 201677-61-4

Sivelestat sodium tetrahydrate - CAS 201677-61-4

SKU:MF-0095045-01

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  • Bioactivity

    Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

  • Target

    Serine Protease, SARS-CoV

  • Related Pathways

    Microbiology/Virology, Proteases/Proteasome

  • CAS Number

    201612

  • Purity

    0.9968

  • Molecular Formula

    C20H29N2NaO11S

  • Molecular Weight

    528.51

  • SMILES

    O.O.O.O.[NaH].CC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(=O)NCC(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound