SJ1461 - CAS 2924546-70-1

SJ1461 is a potent, orally active inhibitor of the BET family, selectively targeting and inhibiting BRD2 (BD1), BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) with respective IC50 values of 1.6 nM, 0.1 nM, 6.5 nM, and 0.2 nM [1].

Epigenetic Reader Domain

Chromatin/Epigenetic

2924475

C21H18ClN7OS2

484

CC=1C2=C(N3C([C@H](CC(NC4=NN=CS4)=O)N=C2C5=CC=C(Cl)C=C5)=NN=C3C)SC1C

-20°C

Ice Packs

Small Compound