SJA6017 - CAS 190274-53-4

SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 (IC50 = 78 nM) . SJA6017 also inhibits cathepsins B (IC50s = 15 nM) and cathepsins L (IC50s = 1.6 nM) . SJA6017 reduces apoptotic cell death, preserves spinal cord tissue and improves functional outcome.

Others, Proteasome

Ubiquitination, Others, Proteases/Proteasome

190274-53-4

C17H25FN2O4S

372.45

S(N[C@H](C(N[C@@H](CC(C)C)C=O)=O)[C@@H](C)C)(=O)(=O)C1=CC=C(F)C=C1

-20°C

Ice Packs

Small Compound