Molfinity
SjDX5-53 - CAS 2767993-73-5
SjDX5-53 - CAS 2767993-73-5
SKU:MF-0127260-01
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Product Details
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Bioactivity
SjDX5-53 is a selective TLR2 inducer derived from a 3 kDa peptide found in Schistosoma japonicum eggs. This compound supports the production and inhibitory function of regulatory T cells (Tregs) by inducing tolerogenic dendritic cells (tolDCs), thereby suppressing inflammatory Th1 and Th17 responses. SjDX5-53 is primarily studied for its therapeutic potential in autoimmune and inflammatory conditions, such as colitis and psoriasis.
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Target
TLR
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Related Pathways
Immunology/Inflammation
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CAS Number
2767993-73-5
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Molecular Formula
C128H208N46O46S3
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Molecular Weight
3223.5
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SMILES
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CCC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CO)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCSC)=O)CCC(N)=O)=O)CC(N)=O)=O)[C@@H](C)O)=O)C)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CO)=O)CCC2)CCC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide