SK-575 - CAS 2523016-96-6

SK-575 is a degradation agent targeting protein-hydrolyzed PARP1 chimera with anticancer and antitumor activity.SK-575 effectively inhibits the growth of cancer cells harboring BRCA1/2 mutations and selectively induces PARP1 degradation in cancer cells.

PROTACs, PARP

PROTAC, DNA Damage/DNA Repair, Chromatin/Epigenetic

2522914

0.9939

C47H53FN8O8

876.97

O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CCN(C(=O)CCCCCCCCCCC(=O)NCCNC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4

-20°C

Ice Packs

PROTAC