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Molfinity

SKA-111 - CAS 1369170-24-0

SKA-111 - CAS 1369170-24-0

MF-0000451-01

$57.84 USD
$41.60 USD $57.84 USD
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Product Details

  • Bioactivity

    SKA-111 is a selective calcium-activated potassium phannel (potassium phannel) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.

  • Target

    Potassium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    1369170-24-0

  • Purity

    0.999

  • Molecular Formula

    C12H10N2S

  • Molecular Weight

    214.29

  • SMILES

    NC1=NC=2C=3C(C(C)=CC2S1)=CC=CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound