SKF83959 - CAS 80751-85-5

SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent variant modulator of the sigma (σ) -1 receptor, which ameliorates cognitive dysfunction for the study depression and Alzheimer's disease.

Sigma receptor, Dopamine Receptor

GPCR/G Protein, Neuroscience

80661

0.9996

C18H20ClNO2

317.81

ClC1=C2C(C(CN(C)CC2)C3=CC(C)=CC=C3)=CC(O)=C1O

-20°C

Ice Packs

Small Compound