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SKI-I - CAS 306301-68-8
SKI-I - CAS 306301-68-8
SKU:MF-0047946-01
Regular price
$853.79 USD
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$853.79 USD
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Product Details
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Bioactivity
SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 μM for ST-hSK, and also inhibits hERK2 (IC50 = 11 μM) . SKI-I induces apoptosis in tumor cell lines.
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Target
Apoptosis, Others, S1P Receptor
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Related Pathways
GPCR/G Protein, Others, Apoptosis
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CAS Number
306225
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Molecular Formula
C25H18N4O2
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Molecular Weight
406.44
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SMILES
Oc1ccc2ccccc2c1\C=N\NC(=O)c1cc([nH]n1)-c1ccc2ccccc2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound