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SKLB 1028 - CAS 1350544-93-2
SKLB 1028 - CAS 1350544-93-2
SKU:MF-0016001-01
Regular price
$48.12 USD
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$48.12 USD
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Product Details
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Bioactivity
SKLB 1028 (Ruserontinib) is a new type of oral multikinase inhibitor of EGFR, FLT3, and Abl. SKLB 1028 shows excellent activity in FLT3-driven AML models and considerable potency in CML models containing Abl mutants.
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Target
EGFR, FLT, Bcr-Abl
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Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling
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CAS Number
1350449
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Purity
0.9999
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Molecular Formula
C24H29N9
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Molecular Weight
443.55
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SMILES
C(C)(C)N1C=2C(N=C1NC=3C=CC=NC3)=CN=C(NC4=CC=C(C=C4)N5CCN(C)CC5)N2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound