SKLB-11A - CAS 433953-86-7

SKLB-11A is a potent allosteric agonist of SIRT3 (sirtuin 3) . It activates signaling pathways associated with autophagy (autophagy), helps prevent mitochondrial dysfunction, and improves cardiac function in models of Doxorubicin-induced cardiotoxicity as well as myocardial ischemia/reperfusion.

Autophagy, Sirtuin

DNA Damage/DNA Repair, Autophagy, Chromatin/Epigenetic

433860

C19H15FN4O2

350.35

O=C(OC)C=1C=2N=C3C=CC=CC3=NC2N(C1N)CC4=CC=C(F)C=C4

-20°C

Ice Packs

Small Compound