SKLB-163 - CAS 1255099-06-9

SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.

Apoptosis, Caspase, Akt, JNK, MAPK, Rho

Proteases/Proteasome, Apoptosis, Cytoskeletal Signaling, MAPK, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint

1255099-06-9

0.9923

C18H16ClN3O2S2

405.92

S(CC(NCC1=CC=CC=C1)=O)C2=NC=3C(S2)=CC(NC(CCl)=O)=CC3

-20°C

Ice Packs

Small Compound