SKQ-1 chloride - CAS 1372443-45-2

SKQ1, also known as Visomitin or plastoquinonyl decyltriphenyl phosphonium (PDTP), is a potent mitochondrial-targeted antioxidant. As the active pharmaceutical ingredient (API) in Visomitin eye drops, SKQ1 exhibits various biomedical activities: (1) prevents impairment of long-term potentiation in rat hippocampal slices caused by amyloid β-protein; (2) reverses aging-related biomarkers in rats; (3) slows age-related degenerative changes in the retinas and choroid of Wistar and OXYS rats; (4) extends the lifespan of male rodents in LP or SPF conditions. SKQ1 can penetrate cell membranes and is proposed for use in anti-aging therapies. Clinical trials for SKQ1 are currently underway in Russia to treat glaucoma. For convenience, SKQ1 is provided as an ethanol-water (1:1, v/v) solution at a concentration of 200 mg/mL.

1372396

C36H42ClO2P

573.14

[Cl-].O=C1C=C(C(=O)C(=C1C)C)CCCCCCCCCC[P+](C=2C=CC=CC2)(C=3C=CC=CC3)C=4C=CC=CC4

-20°C

Ice Packs

Small Compound