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SLP7111228 hydrochloride - CAS 1449768-48-2

SLP7111228 hydrochloride - CAS 1449768-48-2

MF-0120265-01

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Product Details

  • Bioactivity

    SLP7111228 is a potent, selective SPHK1 inhibitor with Ki values of 0.048 μM for SPHK1 and >10 μM for SPH2K, showing a concentration-dependent reduction of sphingosine-1-phosphate (S1P) in U937 cells without affecting sphingosine levels. In vivo, it dose-dependently lowers S1P blood levels in rats.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1449768-48-2

  • Molecular Formula

    C22H34ClN5O

  • Molecular Weight

    420

  • SMILES

    Cl.CCCCCCCCc1ccc(cc1)-c1noc(C[C@@H]2CCCN2C(N)=N)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound