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SMAP-2 - CAS 1809068-70-9
SMAP-2 - CAS 1809068-70-9
SKU:MF-0028791-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .
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Target
Kras, Phosphatase, Ras
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Related Pathways
MAPK, Metabolism
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CAS Number
1808989
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Molecular Formula
C27H27F3N2O4S
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Molecular Weight
532.57
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SMILES
O[C@@H]1[C@H](CCC[C@H]1N1c2ccccc2CCc2ccccc12)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound