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SMAP-2 - CAS 1809068-70-9

SMAP-2 - CAS 1809068-70-9

SKU:MF-0028791-01

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  • Bioactivity

    SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .

  • Target

    Kras, Phosphatase, Ras

  • Related Pathways

    MAPK, Metabolism

  • CAS Number

    1808989

  • Molecular Formula

    C27H27F3N2O4S

  • Molecular Weight

    532.57

  • SMILES

    O[C@@H]1[C@H](CCC[C@H]1N1c2ccccc2CCc2ccccc12)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound