SMO-IN-3 - CAS 2376914-71-3

SMO-IN-3 is a potent inhibitor of smoothened (SMO) that acts on the hedgehog (Hh) signaling pathway (IC50: 34.09 nM) . SMO-IN-3 inhibits the proliferation of Daoy, a human medulloblastoma cell line, and exhibits anticancer effects.

Others, Smo, Hedgehog/Smoothened

Others, Stem Cells, GPCR/G Protein

2376840

C27H25F4N3O2

499.5

C(=O)(C1=C(NC2=CC=CC=C2)C=CC=C1)N3CCC(N(C(=O)C4=C(C(F)(F)F)C=C(F)C=C4)C)CC3

-20°C

Ice Packs

Small Compound