SMU-C68 - CAS 2677039-75-5

SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 μM) . It activates the NF-κB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-α and IL-1β. SMU-C68 holds potential for cancer research applications.

NF-κB, p38 MAPK, TLR

Immunology/Inflammation, MAPK, NF-κB

2676959

C21H21N3O2S2

411.54

O=C(OC(C)C)C1=C(SC2=C1CCC2)NC(=S)NC3=CC=CC4=NC=CC=C43

-20°C

Ice Packs

Small Compound