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Molfinity

Smurf1-IN-A01 - CAS 1007647-73-5

Smurf1-IN-A01 - CAS 1007647-73-5

MF-0012993-01

$33.92 USD
$33.92 USD
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Product Details

  • Bioactivity

    Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (Kd: 3.664 nM) that enhances BMP-2 responsiveness by preventing Smurf1-mediated Smad1/5 degradation.

  • Target

    MyD88, Estrogen Receptor/ERR, Others, HSP, NF-κB, Interleukin

  • Related Pathways

    Cytoskeletal Signaling, Others, NF-κB, Metabolism, Endocrinology/Hormones, Immunology/Inflammation

  • CAS Number

    1007569

  • Purity

    0.9954

  • Molecular Formula

    C22H20ClF3N4O3S

  • Molecular Weight

    512.93

  • SMILES

    Cc1ccnn1-c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound