SMW139 - CAS 2133010-38-3

SMW139 is a selective allosteric antagonist of the P2X7 receptor, exhibiting a Ki value of 32 nM for human P2X7R. In rat liver microsomes, its half-life is 47 minutes. SMW139 is applicable in research related to inflammation, Alzheimer's disease, and multiple sclerosis.

P2X Receptor, Interleukin

Immunology/Inflammation, Neuroscience, Membrane transporter/Ion channel

2132969

C19H21ClF3NO2

387.824

O=C(NCC12CC3(F)CC(F)(CC(F)(C3)C1)C2)C4=CC(OC)=CC=C4Cl

-20°C

Ice Packs

Small Compound