SN-28049 - CAS 492472-30-7

SN-28049 SN is a DNA intercalating drug that binds selectively to GC-rich DNA and shows curative activity against the Colon 38 adenocarcinoma in mice. SN 28049 has a complex action that may involve poisoning of topo IIalpha, suppression of topo I and inhibition of gene transcription from promoters with SP-1 sites. These actions may contribute to the promising experimental solid tumour anticancer activity of SN 28049.

Others

Others

492435

C19H22N4O2

338.4

C(NCCN(C)C)(=O)C=1C=2C(=CC3=C(N2)C(C)=CC=C3)C(=O)N(C)C1

-20°C

Ice Packs

Small Compound