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Molfinity

SN-38-d3 - CAS 718612-49-8

SN-38-d3 - CAS 718612-49-8

MF-0100561-01

$2,787.80 USD
$2,787.80 USD
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Product Details

  • Bioactivity

    SN-38-d3 is a deuterated form of SN-38. As the active metabolite of the topoisomerase I (TopoisomeraseI) inhibitor irinotecan, SN-38 (NK012) notably inhibits the synthesis of DNA and RNA, with IC50 values of 0.077 and 1.3 μM, respectively.

  • Target

    ADC Cytotoxin

  • Related Pathways

    Antibody-drug Conjugate/ADC Related

  • CAS Number

    718612-49-8

  • Molecular Formula

    C22H20N2O5

  • Molecular Weight

    395.42

  • SMILES

    C(C([2H])([2H])[2H])C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(O)=CC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Isotope products