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SN38-COOH - CAS 2170118-23-5
SN38-COOH - CAS 2170118-23-5
SKU:MF-0156402-01
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Product Details
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Bioactivity
SN38-COOH, the active metabolite of the topoisomerase I inhibitor irinotecan, is utilized in the synthesis of antibody-drug conjugates (ADCs) . It functions by inhibiting DNA and RNA synthesis [1] [2].
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Target
Drug-Linker Conjugates for ADC
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
2170090
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Molecular Formula
C26H24N2O8
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Molecular Weight
492.48
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SMILES
O(C(CCC(O)=O)=O)[C@@]1(CC)C2=C(C(=O)N3C(=C2)C=4C(C3)=C(CC)C=5C(N4)=CC=C(O)C5)COC1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound