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Molfinity

SN38-COOH - CAS 2170118-23-5

SN38-COOH - CAS 2170118-23-5

SKU:MF-0156402-01

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  • Bioactivity

    SN38-COOH, the active metabolite of the topoisomerase I inhibitor irinotecan, is utilized in the synthesis of antibody-drug conjugates (ADCs) . It functions by inhibiting DNA and RNA synthesis [1] [2].

  • Target

    Drug-Linker Conjugates for ADC

  • Related Pathways

    Antibody-drug Conjugate/ADC Related

  • CAS Number

    2170090

  • Molecular Formula

    C26H24N2O8

  • Molecular Weight

    492.48

  • SMILES

    O(C(CCC(O)=O)=O)[C@@]1(CC)C2=C(C(=O)N3C(=C2)C=4C(C3)=C(CC)C=5C(N4)=CC=C(O)C5)COC1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound