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SNDX-5613 - CAS 2169919-21-3

SNDX-5613 - CAS 2169919-21-3

SKU:MF-0018810-01

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  • Bioactivity

    Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction with Ki of 0.149 nM and IC50 between 10 and 20 nM, which can be used in the study of acute leukemia with MLL gene rearrangement.

  • Target

    Histone Methyltransferase, Epigenetic Reader Domain

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    2169895

  • Purity

    0.9974

  • Molecular Formula

    C32H47FN6O4S

  • Molecular Weight

    630.82

  • SMILES

    CCN(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@H]1CC[C@@H](CC1)NS(=O)(=O)CC)CC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound