SNJ-1945 - CAS 854402-59-8

SNJ-1945 is a calpain inhibitor with more favorable retinal penetration, high oral bioavailability, and long half-life. SNJ1945 rescued defective function in lissencephaly. SNJ-1945 protects SH-SY5Y cells against MPP (+) and rotenone. SNJ-1945 reduces murine retinal cell death in vitro and in vivo. SNJ-1945 has good aqueous solubility, can prevents the heart from KCl arrest-reperfusion injury associated with the impairment of total Ca (2+) handling by inhibiting the proteolysis of alpha-fodrin as a cardioplegia.

Others

Others

854335

C25H37N3O7

491.58

[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC(OCCOCCOC)=O)CC(C)C)=O)C(C(NC2CC2)=O)=O

-20°C

Ice Packs

Small Compound