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SOF-436 - CAS 2224491-20-5

SOF-436 - CAS 2224491-20-5

SKU:MF-0114678-01

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  • Bioactivity

    SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.

  • Target

    Ras

  • Related Pathways

    GPCR/G Protein, MAPK

  • CAS Number

    2224466

  • Molecular Formula

    C15H13F2NO4S2

  • Molecular Weight

    373.395

  • SMILES

    O=S(=O)(F)C1=CC=CC(=C1)S(=O)(=O)NC2=CC=C(C(F)=C2)C3CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound