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SOF-436 - CAS 2224491-20-5
SOF-436 - CAS 2224491-20-5
SKU:MF-0114678-01
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Product Details
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Bioactivity
SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.
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Target
Ras
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Related Pathways
GPCR/G Protein, MAPK
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CAS Number
2224466
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Molecular Formula
C15H13F2NO4S2
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Molecular Weight
373.395
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SMILES
O=S(=O)(F)C1=CC=CC(=C1)S(=O)(=O)NC2=CC=C(C(F)=C2)C3CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound