Soficitinib - CAS 2574524-67-5

Soficitinib (Compound 20) is a selective inhibitor targeting tyrosine kinase 2 (TYK2) and Janus kinase 2 (JAK2), with IC50 values of 0.5 nM and 1.2 nM, respectively. It holds potential for research in autoimmune diseases such as psoriasis and rheumatoid arthritis, as well as inflammatory conditions.

JAK

Chromatin/Epigenetic, Stem Cells, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

2574452

C18H21ClN8O

400.87

C[C@]12[C@](CN(C1)C3=NC(NC=4C=NN(C)C4)=NC=C3Cl)(CN(C(CC#N)=O)C2)[H]

-20°C

Ice Packs

Small Compound