Sophoflavescenol - CAS 216450-65-6

Sophoflavescenol is a mixed inhibitor of PDE5 with a K (i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells.

Beta-Secretase, Cholinesterase (ChE), BACE, PDE, AChR

Metabolism, Neuroscience

216379

0.9965

C21H20O6

368.38

COc1cc(O)c(CC=C(C)C)c2oc(c(O)c(=O)c12)-c1ccc(O)cc1

-20°C

Ice Packs

Natural Product