Sorafenib-d4 - CAS 1207560-07-3

Sorafenib D4 is the deuterium labeled Sorafenib. Sorafenib is an inhibitor of multikinase (Raf-1, B-Raf, and VEGFR-3 IC50s of 6 nM, 20 nM, and 22 nM, respectively) .

Ferroptosis, FLT, VEGFR, Apoptosis, Raf, Autophagy

Tyrosine Kinase/Adaptors, Autophagy, Apoptosis, Angiogenesis, MAPK

1207560-07-3

C21H16ClF3N4O3

468.85

O(C=1C=C(C(NC)=O)N=CC1)C2=C(C(=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C(=C2[2H])[2H])[2H])[2H]

-20°C

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