SOS1-IN-14 - CAS 2793405-20-4

SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM) . sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.

Ras, Others, Kras

MAPK, GPCR/G Protein, Others

2793381

C29H29F3N6O2

550.57

[H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)C1(CC1)C#N

-20°C

Ice Packs

Small Compound