SP-471P - CAS 2768011-36-3

SP-471P is a potent inhibitor of dengue virus (DENV) protease, exhibiting half-maximal effective concentrations (EC50) of 5.9 μM for DENV1, 1.4 μM for DENV2, 5.1 μM for DENV3, and 1.7 μM for DENV4, with a cytotoxic concentration (CC50) greater than 100 μM. Additionally, SP-471P effectively reduces DENV viral RNA synthesis [1].

Others, DNA/RNA Synthesis, Anti-infection, Virus Protease

Microbiology/Virology, Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

2767972

C33H26BrN5O2

604.5

BrC1=CC=CC(CN2C3=C(C=C(C4=CC(/C(N)=N/O)=CC=C4)C=C3)C5=C2C=CC(C6=CC(/C(N)=N/O)=CC=C6)=C5)=C1

-20°C

Ice Packs

Small Compound