Sp-8-Br-cGMPS - CAS 153660-03-8

Sp-8-Br-cGMPS, an analogue of cGMP, acts as an agonist for cGMP gated cation channels (CNG channels) with an EC50 of 106.5 μM. While Sp-8-Br-cGMPS can induce currents, it does not stabilize channel open states as effectively as a full agonist.

HCN Channel

Membrane transporter/Ion channel

153660-03-8

C10H11BrN5O6PS

440.17

BrC=1N(C2=C(N1)C(=O)N=C(N)N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(S)O4)[H])[H]

-20°C

Ice Packs

Small Compound