Sp-8-Cl-cAMPS - CAS 142754-28-7

Sp-8-Cl-cAMPS, as a derivative and analogue of cAMP, can inhibit the growth of various human tumor cells, such as leukemia cells HL-60 and colon cancer cells LS-174T, with an IC50 range of 8-100 μM. In addition, this compound can activate protein kinase cAKI and cAKII, with Ka values of 0.25 μM and 3.2 μM, respectively.

Others, PKA

Others, Tyrosine Kinase/Adaptors

142754-28-7

C10H11ClN5O5PS

379.72

ClC=1N(C=2C(N1)=C(N)N=CN2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(S)O4)[H])[H]

-20°C

Ice Packs

Small Compound