Sp-Cyclic AMPS (sodium salt) - CAS 142439-95-0

Sp-cAMPS sodium salt is an analog of cAMP that serves as a potent activator of cAMP-dependent PKA I and PKA II, and as a competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 μM. It also binds the PDE10 GAF domain with an EC50 of 40 μM [1] [2] [3].

Others, PKA, PDE

Metabolism, Tyrosine Kinase/Adaptors, Others

142439-95-0

C10H12N5NaO5PS+

367.25

O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP([S-])(OC2)=O)N3C4=NC=NC(N)=C4N=C3.[Na+]

-20°C

Ice Packs

Small Compound