Molfinity

SP100030 analogue 1 - CAS 154934-68-6

SKU:MF-0122665-01

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Product Details

Bioactivity
SP100030 analogue 1 (compound 11) is a selective transcription activation (SITA) inhibitor within the SP100030 class, capable of inhibiting XPO1-dependent upregulation of IL2 in a Jurkat-based IL2-Luc reporter assay, with an EC50 of 137 nM.
Target
CRM1
Related Pathways
Membrane transporter/Ion channel
CAS Number
154934-68-6
Molecular Formula
C13H5ClF7N3O
Molecular Weight
387.64
SMILES
O=C(NC1=CC(F)=CC(=C1)C(F)(F)F)C2=CN=C(Cl)N=C2C(F)(F)F
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound