SP600125 - CAS 129-56-6

SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.

Ferroptosis, Apoptosis, Autophagy, JNK, Aurora Kinase, Trk receptor

Cell Cycle/Checkpoint, Apoptosis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Autophagy, MAPK

67

0.9982

C14H8N2O

220.23

O=C1C2=C3C(NN=C3C3=C1C=CC=C3)=CC=C2

-20°C

Ice Packs

Small Compound