Molfinity
Sparstolonin B - CAS 1259330-61-4
Sparstolonin B - CAS 1259330-61-4
SKU:MF-0011938-01
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Product Details
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Bioactivity
Sparstolonin B, a selective TLR2 and TLR4 antagonist, is an isocoumarin compound isolated from the tubers of Sparganium stoloniferum and Scirpus yagara with anti-HIV, anticancer, antitumour and anti-inflammatory activities, inhibits selective Toll-like receptors, inhibits free fatty acids It inhibits selective Toll-like receptors, inhibits free fatty acid palmitate-induced chondrocyte inflammation and attenuates post-traumatic arthritis in obese mice, and inhibits lipopolysaccharide-induced inflammation in 3T3-L1 adipocytes, which can be used for validation and mammary carcinoma studies.
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Target
HIV Protease, TLR
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Related Pathways
Microbiology/Virology, Immunology/Inflammation, Proteases/Proteasome
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CAS Number
1259330-61-4
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Purity
0.9954
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Molecular Formula
C15H8O5
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Molecular Weight
268.22
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SMILES
Oc1ccc2oc3ccc(O)c4c3c(coc4=O)c2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product