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Molfinity

SPH3127 - CAS 1399849-02-5

SPH3127 - CAS 1399849-02-5

SKU:MF-0138272-01

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  • Bioactivity

    SPH3127 (DRI 18) is a potent, orally active, novel direct renin inhibitor with IC50 values of 0.4 nM for recombinant human-renin and 0.45 nM for human plasma renin activity. SPH3127 has an anti-hypertensive effect and can be used to study hypertension.

  • Target

    Others, RAAS

  • Related Pathways

    Others, Endocrinology/Hormones

  • CAS Number

    1399849-02-5

  • Molecular Formula

    C22H32N6O4

  • Molecular Weight

    444.53

  • SMILES

    [C@@H](N(C(=O)[C@H]1CNCCO1)C2CC2)(C)C=3C=4C(N(CCCNC(OC)=O)N3)=NC(C)=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound