SPI-05 - CAS 5463-64-9

SPI-05 is a non-competitive inhibitor of SUMO-specific proteases (SENP1/2) with an IC50 of 60 μM. It has potential applications in cancer research, particularly in the study of prostate cancer with SENP1 overexpression and solid tumors driven by hypoxia.

E1/E2/E3 Enzyme

Ubiquitination

5390

C34H26N6O6S2

678.74

O=S(=O)(O)C1=CC(N=NC2=CC=C(N)C=3C=CC=CC23)=CC=C1C=CC4=CC=C(N=NC5=CC=C(N)C=6C=CC=CC56)C=C4S(=O)(=O)O

-20°C

Ice Packs

Small Compound