SPOP-IN-2 - CAS 3031640-86-2

SPOP-IN-2 (Compound E1) is a potent inhibitor of speckle-type POZ protein (SPOP), with an IC50 of 0.58 μM. It disrupts the interaction between SPOP and substrates and selectively inhibits the proliferation of clear cell renal cell carcinoma (ccRCC) .

E1/E2/E3 Enzyme

Ubiquitination

3031552

C15H13ClN2O5S

368.79

C(O)(=O)C=1N2[C@@]([C@H](NC(=O)C=3OC(CCl)=CC3)C2=O)(SCC1C=C)[H]

-20°C

Ice Packs

Small Compound