SPP-DM1 - CAS 452072-20-7

SPP-DM1, a drug-linker conjugate for antibody-drug conjugates (ADC), demonstrates potent antitumor activity. It comprises DM1 (a potent microtubule-disrupting agent) connected through the ADC linker SPP[1].

Drug-Linker Conjugates for ADC

Antibody-drug Conjugate/ADC Related

452045

C44H59ClN4O14S2

967.54

[H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@]([H])(OC(=O)[C@H](C)N(C)C(=O)CCSSC(C)CCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C

-20°C

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