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SPR519 - CAS 1391923-59-3

SPR519 - CAS 1391923-59-3

MF-0145117-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    SPR519 is a potent dual inhibitor of PI3Kα and mTOR kinases with IC50 (PI3Kalpha) = 30 nM and IC50 (mTOR) = 10 nM. SPR519 exhibits an EC50 of low sub-micromolar range among various tested cancer cell lines such as A2780 (0.23 μM), PC3 (0.48 μM), and SKOV3 (0.50 μM) .

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    1391861

  • Molecular Formula

    C19H21N7O3S

  • Molecular Weight

    427.48

  • SMILES

    O(C=1N=C(N=C(N1)N2CCOCC2)C=3SC(N)=NC3)C4=CC=C(C(N(C)C)=O)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound