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SPSB2-iNOS inhibitory cyclic peptide-1 - CAS 1621616-13-4
SPSB2-iNOS inhibitory cyclic peptide-1 - CAS 1621616-13-4
SKU:MF-0126393-01
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Product Details
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Bioactivity
SPSB2-iNOS inhibitory cyclic peptide-1, an inhibitor for the interaction between the SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, binds SPSB2 at the iNOS site with a K D of 4.4 nM. It is resistant to proteases pepsin, trypsin, and α-chymotrypsin and remains stable in human plasma and oxidative environments [1].
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Target
NO Synthase
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Related Pathways
Immunology/Inflammation
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CAS Number
1621616-13-4
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Molecular Formula
C35H56N12O14S2
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Molecular Weight
933.02
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SMILES
[C@@H](CC)(C)[C@]1(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(N)=O)CSSC[C@H](NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N1)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide