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SPSB2-iNOS inhibitory cyclic peptide-2 - CAS 1989528-33-7
SPSB2-iNOS inhibitory cyclic peptide-2 - CAS 1989528-33-7
SKU:MF-0126394-01
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Product Details
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Bioactivity
Compound CP2, also known as SPSB2-iNOS inhibitory cyclic peptide-2, serves as an inhibitor disrupting the interaction between SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS. It binds to the SPSB2 on the iNOS site with an affinity (K D) of 21 nM. This peptide is characterized by its resistance to reduction and oxidative stability [1].
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Target
NO Synthase
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Related Pathways
Immunology/Inflammation
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CAS Number
1989528-33-7
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Molecular Formula
C36H49N11O12
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Molecular Weight
827.84
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SMILES
C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCC(=O)N3)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide