SQA1 - CAS 1255915-27-5

SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.

CCR, CXCR

GPCR/G Protein, Microbiology/Virology, Autophagy, Immunology/Inflammation

1255915-27-5

C22H26N4O5

426.47

N(C1=C(N[C@H](CC)C2=CC(C(C)C)=CO2)C(=O)C1=O)C=3C(O)=C(C(N(C)C)=O)N=CC3

-20°C

Ice Packs

Small Compound