SQLE-IN-1 - CAS 1019169-83-5

SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the expression of the tumor suppressor gene PTEN. expression, inhibiting the protein expression of PI3K and AKT.

Akt, PTEN, PI3K, Antifungal

Microbiology/Virology, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

1019169-83-5

0.9989

C24H21F2N5O2S

481.52

O=S(=O)(NC1=CC=C(C=C1)NC=2N=C(N=C(C2)NC3=CC=C(C=C3)C)C)C4=CC=C(F)C=C4F

-20°C

Ice Packs

Small Compound