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Molfinity

SR-1277 - CAS 1446715-47-4

SR-1277 - CAS 1446715-47-4

SKU:MF-0012128-01

Regular price $345.72 USD
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  • Bioactivity

    SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1δ plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.

  • Target

    Casein Kinase

  • Related Pathways

    Stem Cells, Metabolism

  • CAS Number

    1446715-47-4

  • Molecular Formula

    C21H19N9O3S

  • Molecular Weight

    477.5

  • SMILES

    O=[N+](C1=CC=CC2=C1NC(CNC3=NC(N4CCOCC4)=NC5=C3N=CN5C6=CSC=C6)=N2)[O-]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound