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SR-1277 - CAS 1446715-47-4
SR-1277 - CAS 1446715-47-4
SKU:MF-0012128-01
Regular price
$345.72 USD
Regular price
$219.05 USD
Sale price
$345.72 USD
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Product Details
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Bioactivity
SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1δ plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.
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Target
Casein Kinase
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Related Pathways
Stem Cells, Metabolism
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CAS Number
1446715-47-4
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Molecular Formula
C21H19N9O3S
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Molecular Weight
477.5
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SMILES
O=[N+](C1=CC=CC2=C1NC(CNC3=NC(N4CCOCC4)=NC5=C3N=CN5C6=CSC=C6)=N2)[O-]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound