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SR-2890 - CAS 1454584-91-8
SR-2890 - CAS 1454584-91-8
SKU:MF-0097929-01
Regular price
$221.11 USD
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$221.11 USD
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Product Details
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Bioactivity
SR-2890 is a potent and highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with an IC50 of 4 nM for CK1δ. This compound inhibits melanoma A375 cell growth with an EC50 of 38 nM in MTT assays and possesses pharmacokinetic properties suitable for xenograft studies using human cancer cell lines.
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Target
Casein Kinase
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Related Pathways
Stem Cells, Metabolism
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CAS Number
1454485
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Purity
0.991
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Molecular Formula
C23H21ClFN9
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Molecular Weight
477.93
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SMILES
FC1=CC=CC(=C1)N2C=NC=3C(=NC(=NC32)N4CCNCC4)NCC5=NC=6C=CC(Cl)=CC6N5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound