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SR-717 free acid - CAS 2375420-34-9
SR-717 free acid - CAS 2375420-34-9
SKU:MF-0152801-01
Regular price
$234.28 USD
Regular price
Sale price
$234.28 USD
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Product Details
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Bioactivity
SR-717 free acid is a stable cGAMP mimetic and non-nucleotide STING agonist, demonstrating antitumor activity with EC50 values of 2.1 μM in ISG-THP1 (WT) and 2.2 μM in ISG-THP1 cGAS KO (cGAS KO) cell lines.
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Target
Others, STING
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Related Pathways
Immunology/Inflammation, Others
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CAS Number
2375377
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Molecular Formula
C15H9F2N5O3
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Molecular Weight
345.266
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SMILES
OC(=O)c1cc(F)c(F)cc1NC(=O)c1ccc(nn1)-n1ccnc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound