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Molfinity

SR12343 - CAS 2055101-86-3

SR12343 - CAS 2055101-86-3

MF-0095523-01

$51.86 USD
$51.86 USD
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Product Details

  • Bioactivity

    SR12343 is a small molecule inhibitor of the IKK/NF-κB signaling pathway that functions as a NEMO-binding domain (NBD) mimetic. SR12343 inhibits NF-κB activation with an IC50 of 37.02 μM by specifically blocking the critical IKKβ-NEMO interaction, reduces pulmonary inflammation in models, and is suitable for research into inflammatory and degenerative diseases.

  • Target

    IκB/IKK, NF-κB

  • Related Pathways

    NF-κB

  • CAS Number

    2055101-86-3

  • Purity

    0.9991

  • Molecular Formula

    C15H15BrClN3O

  • Molecular Weight

    368.66

  • SMILES

    O=C(NCCC=1C=CC=C(Br)C1)CNC2=NC=C(Cl)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound